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Although clindamycin, erythromycin, and chloramphenicol are not structurally linked, they act at sites in close vicinity, and binding by one of these antibiotics to the ribosome may inhibit the interaction of the others.

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inflammation or damage to the nerves causing numbness, tingling, pain or muscle weakness blurring, inflammation or temporary loss of vision chloramphenicol may slow down development of immunity, and you may develop infections more frequently, which are difficult to fight off.

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the use of the following drugs may interfere with the activity of chloramphenicol .

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methotrexate is bound in part to serum albumin after absorption, and toxicity may be increased because of displacement by certain drugs such as salicylates, sulphonamides, phenytoin, and some antibacterials such as tetracycline, chloramphenicol and para-aminobenzoic acid.

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seven hundred and fifty-five genes were differentially expressed on chloramphenicol treatment 364 genes were up-regulated and 391 were down-regulated.


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