It concluded that mefloquine prophylaxis with a loading dose should be considered for short term adult travellers or military personnel going to malarious areas where there is chloroquine resistance.
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given the low level of efficacy of chloroquine, the frequent side effects of chloroquine therapy, and the low rate of compliance associated with quinine therapy, alternatives are urgently needed.
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chloroquine-resistant plasmodium falciparum and p vivax 100 mg orally twice a day for 7 days plus quinine sulfate 650 mg every 8 hours for 3 to 7 days.
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like chloroquine phosphate, usp, plaquenil is highly active against the erythrocytic forms of p.
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